Drug Name】Compound Platycodonopsis loquat syrup

[Ingredients] This product is a compound preparation, the composition is: each bottle contains 4 grams of Platycodon grandiflorum flow paste, flow paste 6 grams, 1 gram of ammonium chloride, guaiacol glycerol ether 0.8 grams, isopropylzine hydrochloride 0.03 grams, 0.35 grams of acid, 0.5 grams of sodium citrate, tincture of orange peel 1 milliliter.

Properties]: This product is a light brown translucent viscous liquid; slightly aromatic gas.

【Indications】Expectorant cough and asthma. For the treatment of pediatric phlegm, cough, bronchitis.

Specifications]: Compound.

Usage and dosage】Orally: 1~6 months, 2ml; 6 months~1 year old, 3ml; 1~2 years old, 5ml; 2~4 years old, 8ml; 4~7 years old, 10ml; 3 times a day.

Adverse effects: Occasional palpitations, fever, sweating, etc., which may disappear after a few moments of rest.

Contraindications] Not yet clear.

[Precautions] Not yet clear.

Pregnant and lactating women】It is not clear.

Children] is not clear.

Elderly] It is not clear.

Drug interactions] is not clear.

Overdose] is unclear.

Pharmacology and Toxicology] This product can act directly on the adrenergic receptor, the a and B receptors are agonistic; can effectively relax the bronchial smooth muscle, so that the bronchial mucosal vasoconstriction, reduce congestion and edema, is conducive to improving the obstruction of small airways. Its mechanism of action mainly inhibits the cough center, but also has H receptor blocking effect, relieve bronchial smooth muscle spasm and bronchial mucosal congestion and edema; can increase the secretion of respiratory mucus, sputum dilution, prompting its discharge, has a strong cough suppressant effect; blocking lung - pleural baroreceptors produced by pulmonary - vagal reflexes, and poppy alkaloid-like release of smooth muscle spasms, and at the same time, with central and peripheral dual mechanism of cough suppression. It has both central and peripheral dual mechanism of cough suppression.

Pharmacokinetics] The product is absorbed from the intestine after oral administration, and can enter the cerebrospinal fluid through the blood-brain barrier.Vd is 3~4L/kg.Most of the product is oxidized and metabolized after absorption, and a small amount of about 21% is excreted through urine. The effect is long lasting, ti is 3~4 hours.

Storage]: Keep sealed in a cool place (not more than 20°C). In polyester bottle, 100ml/bottle.

Effective period: 24 months.

Implementation】National Drug Standard WS-10001-(HD-1168)-2002

Approval Number]: National Pharmaceutical Standard H20073291